Based on conversations with hundreds of people who've gone through this:
Week 1-2: You might not notice much. Some people report slightly less burning on an empty stomach. Others notice nothing yet. This is normal - cellular pathway activation takes time.
Week 3-4: This is usually when people first think "wait, something's different." Less bloating after meals. Reduced anxiety about eating. The constant low-grade discomfort starts lifting. One patient told me "I realized I'd gotten through a whole day without thinking about my stomach."
Week 6-8: For many people, this is when it clicks. They can eat foods they'd been avoiding for months. The burning is gone or dramatically reduced. Energy improves because they're not in constant low-grade inflammation. They start to trust their body again.
Week 12+: People often report feeling better than they did even before H. pylori. Their stomach is genuinely healed, not just managed. They're not hypervigilant about every meal. They can travel, eat at restaurants, live normally.
Not everyone's timeline is identical. If you had severe gastritis or an ulcer, it may take longer. If you've dealt with this for years, healing won't happen overnight.
But the consistent pattern I've seen: when people actually reactivate their stomach's healing mechanisms instead of just managing symptoms, they get to a place they'd stopped believing was possible.